After the deadly shooting of last season, Van In and his team are desperately trying to find evidence against Antoon Coninckx. The story shifts when Coninckx himself comes asking the police for help.
Van In and his team are asked investigate the disappearance of a young and wealthy woman. Since she has put her house for sale, they believe she just wanted to start a new life. However, a local fisherman soon discovers her corpse.
The husband of medical examiner Vanmaele's mistress gets murdered. The doctor soon turns himself into the prime suspect. Meanwhile, the untimely demise of Jelle Cockx makes detective Tom Smeekens fail to get back to work.
A short time after the release of a suspected pedophile, a young girl gets kidnapped in the exact same circumstances as the unresolved case. Detective Rob De Maegd does not seem to get along with Dirk Vereecke, his new police partner.
The murder of a teenage drug addict leads Van In and his team to investigate the past of their new colleague Dirk Vereecke. They soon discover a connection between this case and the prior disappearance of Vereecke's girlfriend.
A young and talented swimmer finds her coach hung. The girl's father is the prime suspect, until an intrusive police academy student shares a different theory. Meanwhile, detective Rudy Snels joins the team of Van In.
The CEO of an electronics company ends up in a coma after a violent carjacking. Blood traces in his recovered car lead the police to the corpse of his secretary. Commissioner De Kee takes a decision about the lazy detective Rudy Snels.
The bodies of multiple women are found in a field. They each show human bite marks and broken teeth. Carine Neels rejoins the team of Van In and helps her colleagues to connect the victims to a local dentist. Hannelore ends up in danger.
A young guy dies suddenly from what appears to be a drug overdose. The medical investigation however shows his cocaine was poisoned. Guido Versavel suddenly announces his return to the team of Van In. Robert De Maegd takes a big decision.
A few businessmen and their wives meet up in a local hotel to have a so-called 'key party', involving sexual partner switches. The next morning, one of the men is found murdered. Van In finally makes his choice between Eva and Hannelore.
The team suspects a drug dealer to have killed one of his female clients. The victim however seems to have had multiple enemies. Neels gets along pretty fine with Eric Vranckx, her new police partner. Versavel has a mysterious appointment.
Guido Versavel is secretly infiltrating into a mysterious sect, when a murder case obliges him to blow his cover. Van In is disturbed because he was not taken into Versavel's confidence. Commissioner De Kee announces his retirement.
Van In's daughter is kidnapped. Everyone is sure of a good outcome, until every track is lost. De Kee believes there is a mole inside his team. Time is running out, as the sect is about to perform its yearly sacrifice of a young virgin.
