- Pat O'Brien
- Father Peter J. Dunne
- Darryl Hickman
- Matt Davis
- Charles Kemper
- Emmett Mulvey
- Una O'Connor
- Miss O'Rourke
- Arthur Shields
- Mr. Michael O'Donnell
- Harry Shannon
- Thomas Lee, Lawyer
- Joe Sawyer
- Steve Davis
- Anna Q. Nilsson
- Mrs. Olaf Knudson
- Donn Gift
- Jimmy
- Myrna Dell
- Paula Hendricks
- Ruth Donnelly
- Kate Mulvey
- James Nolan
- Policeman Danny Briggs
- Billy Cummings
- Tony
- Billy Gray
- Chip
- Eric Roberts
- Monk
- Gene Collins
- Lefty
- Lester Matthews
- Archbishop John Joseph Glennon
- Griff Barnett
- Governor
- Jason Robards Sr.
- J.J. Sonin
- Rudy Wissler
- Boy Soloist
- Ernie Adams
- Newspaper Supplier on Loading Dock
- Sedal Bennett
- Blowsy Woman
- Ricky Berger
- Boy
- Stanley Blystone
- Policeman
- Robert Bray
- Classroom Instructor
- Ralph Brooks
- Bed-Delivery Man
- Leon Burbank
- Ed
- Raymond Burr
- Prosecuting Attorney in Montage
- Freddie Chapman
- Roger Sylvestor
- Robert Clarke
- Priest
- Florence Clayton
- Blowsy Woman
- Tom Coleman
- Newspaper Vendor
- Ellen Corby
- Colpeck's Secretary
- Paul Dunn
- Harry
- Ralph Dunn
- Workman
- Dot Farley
- Mrs. Monohan
- Frank Ferguson
- M.R. Colpeck
- Charles Flynn
- Workman
- Bobby Frasco
- Pat
- Jack Gargan
- Policeman
- Vincent Graeff
- Pete 'Petey' Hendricks
- Don Haggerty
- Gorilla Blake
- Harry Harvey
- Dr. Adams
- Timmy Hawkins
- Urchin Boy at end of movie
- Harry Hayden
- Mr. Dunfee
- Gene Holland
- Art
- Wesley Hopper
- Guard
- Leo Kaye
- Newspaper Vendor
- Perc Launders
- Policeman
- Gerald Mackey
- Blackie
- George McDonald
- Mickey Pulaski
- Charles Miller
- Judge
- Philip Morris
- Prison Guard
- Broderick O'Farrell
- Butler
- Anne O'Neal
- Mrs. O'Flaherty
- Albert Ray
- Boy
- Lanny Rees
- Boy
- Buddy Roosevelt
- Pedestrian
- Harold Smith
- Hoodlum
- Cedric Stevens
- Clerk
- Tex Swan
- Driver
- Emmett Vogan
- Matt's Defense Attorney
- Sid Wagner
- Swede
- Ray Walker
- Fred Carver - Off-Screen Storyteller
