A six-time Emmy Award winner, Kelsey Grammer was born in Saint Thomas, U.S. Virgin Islands, to Sally (Cranmer), a singer, and Frank Allen Grammer, Jr., a musician and restaurateur, who were from the mainland. He was raised in New Jersey and Florida. Grammer was drawn to the works of William Shakespeare and spent two years at the prestigious Juilliard School. He then dove into the world of regional theater, eventually making the leap to Broadway with roles in "Macbeth" and "Othello." He joined the cast of the situation comedy Cheers (1982) in 1984.

Grammer is the first actor in television history to receive multiple Emmy nominations for performing the same role on three series. He received two nominations for his original portrayal of Dr. Frasier Crane on Cheers (1982), another for his guest appearance in that role on Wings (1990), and nine nominations (earning four awards) as Outstanding Actor for his work on Frasier (1993). Over the years, Dr. Frasier Crane has become one of television's most endearing and enduring characters. In addition to his Emmy Awards, Grammer has won two Golden Globe Awards, two American Comedy Awards and a People's Choice Award for his portrait. Grammer's distinctive voice has been heard in several hit animated features, including the voice of Stinky Pete in Disney's hit Toy Story 2 (1999) and a role in Anastasia (1997). On television, he has also been seen in several mini-series and movies. In 1996, he hosted an hour-long salute to Jack Benny for which he served as executive producer. He also starred in HBO's award-winning comedy The Pentagon Wars (1998). Grammer's autobiography, "So Far," was published in fall 1995.