Carol is thrilled to get a job at a local newspaper, until she discovers that it is a job to chauffeur around the paper's teenage reporter. Charley and Laverne begin to spend a lot of time together, sparking rumours to fly.
When Mrs. Hillary Clinton is scheduled to tour the clinic Carol is determined to get a meeting with her. But her trouble only lands her in jail along with Laverne and Charley.
After a number of failed new careers Charley tries his hand at stand-up comedy which is based on making fun of Harry whilst doing so. Maxine fights the bus company when they move the bus shelter.
Charley discovers that a 17 year old flutist he meets just happens to be his son. Carol takes over for the day for Laverne and while there she tries to get Maxine to stop smoking.
While Laverne is still away, shy Doris, now a qualified nurse, is back to fill in for her. Meanwhile, Harry gets upset when Sophia moves in and brings her Shady Pines friends with her.
The Canal Street clinic applies for a grant and is evaluated, when the man leaves his notebook Maxine takes it and reads it. Sophia gives Charley advice on how to impress his Italia girlfriends parents.
Charley is dating a new minister and brings her by the Weston's place, Harry quickly finds himself attracted to her. Meanwhile Laverne sells her beloved truck to Maxine.
Charley has a good looking new roommate, who he hopes will help him meet more women. Although there is something Charley hasn't yet figured out about him. Meanwhile, Harry invites Maxine to join him and two friends in a golfing foursome.
Carol believes a man she been dating since they met in a museum is the same man who has been writing letters to the "Aunt Martha" column in her newspaper. Meanwhile and old sparring partner of Harry's shows up with a score to settle.
Charley fearing his own mortality after a recent death causes him to feel depressed. Carol does her best to boost his moral by staging a funeral for him.
After having to get gall bladder surgery a patient asks Maxine to take care of her children while she is under the knife. Harry is invited to the Shady Pines square dance by Sophia.
While at the park with Scotty, Harry becomes smitten with a woman there with her granddaughter. Laverne finds a parrot and brings it to the office. Carol becomes obsessed with shopping at discount clubs.
Laverne has a handsome childhood friend visit from back home. Of course, Carol becomes interested in him. Charley is asked to pose for pictures in a magazine.
Carol becomes jealous of her new boyfriend Kevin when he bonds so quicky with her son Scotty. Meanwhile, Laverne decides to learn the Spanish language.
Much to Charley's dismay Harry becomes Carol's boss' new best friend which makes him extremely jealous. Laverne decides to audition for a part in a commercial where she will play the voice of a cartoon owl.
Carol meets Kevin's beautiful and intelligent ex-wife which leads her to believe that there relationship is over. Charley eats some old Chinese food from the Weston's fridge and get sick so he decides to sue Harry.
Matt and Laverne's relationship keeps getting interrupted with prompts her to go out with Maxine, Charley and his friend Bud, she quickly hits it off with him. Harry meets a woman who has a female dog that looks a lot like Dreyfuss so he asks her to breed the two.
Wedding preparations become frustrating for Laverne. Harry makes plans to move to Vermont which upsets Carol. Sophia and Charley drive to Hickory for Laverne's wedding.
Laverne runs away to elope while Kevin shows up in Hickory to make up with Carol. Harry gets an offer on the house. Barbara comes to visit to help the family pack.
While Harry sets off for a vacation in the wilderness of Montana (having unwittingly invited Charley to join him), Carol decides it's time to find a new friend. Meanwhile, Laverne and Maxine make friends with a psychic.