The award-winning series returns charting the day-to-day life of seven NHS Trusts across the city of Liverpool. Operating theatres shut but emergencies continue to arrive as patients are caught up in an extraordinary hospital move.
In Aintree Hospital's major trauma centre, a 15-strong team try to save the life of a young man who has been stabbed in the chest - one of three stabbings to arrive during the day. A homeless man is given an ultimatum by hospital staff.
On one dramatic day at Liverpool Heart and Chest Hospital - Friday 13th - three patients, two of them, the most complex the hospital treats in a year, are facing their own mortality and hoping for life-changing operations.
As medical advances save children who a decade ago may not have survived, Alder Hey Children's Hospital faces the challenge of providing ongoing care for these complex patients.
With NHS 'bed blocking' numbers at their highest level since 2017, Liverpool's hospitals are struggling to discharge patients because of a lack of care in the community.
At the UK's only specialist neurology hospital Trust, a doctor strives to secure groundbreaking treatment for patients with a misunderstood but common neurological disorder.
Alder Hey Children's Hospital is home to a world-renowned craniofacial department, one of only 4 in the UK treating life-threatening congenital skull and facial abnormalities.
As medical advances cure patients with cancer, who a decade ago may not have survived, doctors face the challenge of using newer therapies which are not without risk.
Filmed inside the Royal Free London from the first day of the lockdown. With beds in the hospital rapidly filling with Covid-positive patients, doctors are redeployed and ICU doubles its capacity.
The pandemic is approaching its peak and most of the Royal Free London's beds are now filled with coronavirus patients. But with ten per cent of the workforce off sick or self-isolating, it is challenging to provide safe staffing levels.