When Kate has to unexpectedly go in to work, she has no choice but to leave ALF in charge of the baby. While babysitting, ALF faces a huge dilemma when he goes outside and finds the baby missing.
ALF is accidentally photographed by a tabloid photographer. ALF sneaks into their van to eat the film while Willie uses his memory of Star Trek episodes to make up extraterrestrial stories, whose credulity actually amazes the paparazzi.
When the Tanners' cat Lucky dies, ALF decides to answer a giveaway ad in the paper for kittens so that he can eat them, only to find out that he likes having them as pets.
Alf thinks he's a stand-up comedian. NBC offers him a show, he's famous and rich and everybody loves him. In his dream he sends Willie and Kate to the attic, where they usually send him.
With Willie and Kate going out for the night, ALF sneaks into a retirement home in the hopes of meeting a once-famous actress, whose glory days are far behind her.
Fearing that he might "internally blow up" due to his high calorie consumption, ALF decides to cut meat from his diet. However after a few days, ALF turns into a "wolf" and steals the Tanner's car in an effort to hunt for food.
ALF hears from his friends Skip and Rhonda, who have established the colony of New Melmac and invite ALF to live with them. But when the Air Force's Alien Task Force finally capture ALF as he is about to depart Earth, is all hope lost?
