Walt's world crumbles even more after finding out that Skyler is cheating on him. Jesse tries to set up a meeting with Gus to try and sell his own version of the blue meth. Meanwhile, Hank is growing obsessed with finding Heisenberg.
As Skyler reconsiders her objections to Walt's return, he mulls over returning to the drug trade. Meanwhile, Hank's obsession promises trouble for Jesse.
Heisenberg's organized and practical assistant Gale greatly aids his work in Gus's lab. Hank finally tracks the RV back to Jesse, as a concerned Walt finds any way to erase the evidence.
Skyler hatches a plan as Hank's hospital bills stack up. Meanwhile, Walt and Gus come to a better understanding as Jesse, looking for more independence, pursues a new opportunity.
Skyler gets more involved in Walt's business, much to his chagrin, as Hank struggles with his recovery. Meanwhile, Jesse takes an active role in his new enterprise, leading him to a startling discovery.
Against Walt's advice, Jesse lashes out. Fearing for Jesse's safety, Walt takes drastic action to intervene. Meanwhile a tragic event leads to a shocking confrontation.
Jesse has disappeared and Walt is in big trouble with Gus. So Gus rehires Gale to learn from Walt's cooking so that they can dispose of Walt once and for all.
