16 of the best female 125-pounders in the world compete for the inaugural UFC flyweight belt. Coaches Eddie Alvarez and Justin Gaethje pick teams, seeded in a tournament format. After teams begin training, the first fight kicks takes place.
Justin Gaethje struggles to communicate with an international fighter. An injury during a training session puts a competitor's future in doubt. Then an experienced flyweight takes on a dark horse in the second preliminary fight.
The teams step away from the TUF gym to train at the new UFC Performance Institute. One of the fighters has an emotional breakdown during practice. Then, it's the third preliminary fight with a spot in the quarterfinals on the line.
Two top-seeded teammates discuss the possibility of having to face each other later in the tournament. A fighter shares the story of her lifelong battle with addiction. Then, a heavily favored veteran takes on an underdog in the fourth preliminary fight.
After losing in the Octagon one of the fighters skips training, causing a rift between her and her coach. Then, two flyweights face off in the fifth preliminary fight.
Eddie Alvarez pulls out all the stops to give his team a competitive advantage. A fighter struggles with an old injury. Then, one of the most accomplished fighters in the tournament takes on a young rising star in the sixth preliminary fight.
Lauren Murphy's strained relationship with Coach Alvarez reaches a tipping point. Eddie and Justin go head to head in the coaches challenge. Then, two flyweights face off in the eighth preliminary fight with the last quarterfinal spot on the line.
Before the quarterfinals kick off, both teams enjoy a night out on Lake Las Vegas. One fighter struggles with a difficult weight cut, putting her future in the competition in doubt. Then, it's the first two quarterfinal fights.
Four female flyweights compete in the last two quarterfinals in an action-packed episode. The winners advance to the semifinals and face off against their next opponents.
As training continues in preparation for the semifinals, the coaches engage in a prank war. Then, two flyweights take to the Octagon to face off in the first semifinal fight.
In the last episode of the season before the live finale, a fighter turns to the UFC Performance Institute for help with her weight cut. Then, the second semifinal determines which flyweight moves on to the championship fight.