Not wanting to go to the dentist, Spike has Tom and Jerry remove his tooth with weird results. It's Picture Day, and Jerry tries to get Tuffy ready as Ginger gets Tom and Spike ready as well. Jerry befriends a cricket who is causing trouble for Tom.
Tom, Spike and Tyke are followed and chased by a rain cloud. When the cloud disappears, Jerry and Tuffy fool them by pretending it's still raining; Rick orders the "Suck-Up" machine from a commercial on T.V.; Tom and Jerry both mess around with it; Little Quacker thinks he's the cause of Tom, Jerry and Spike's misfortunes after he walks under a ladder.
Tom is determined to hijack the fun Jerry and Tuffy are having with making paper airplanes. Tom's hijinks take a turn for the worse when he realizes he's made a paper airplane out of Ginger's great-great grandmother's treasured fruitcake recipe.
Toodles' folks are coming for a visit. Problem is they think she's married with kittens. Tom plays the role of husband and volunteers Jerry and Tuffy to play their kittens.
When Hildie and Beatie believe they had a few of their things stolen, they use a little magic to create Bog, the Cottage Beast. The new addition makes Tom and Jerry wish they had copped to using the stolen goods to beat up on each other.
The witch sisters are brewing their latest concoction. As they put the ingredients into the cauldron, they discover the walnuts has disappeared. Jerry's enjoying the nuts. They blame Tom and send him out to gather nuts for the potion.
Butch and Meathead don't want to miss a marathon of their favorite show so they make a deal with Tom to trade TV time for a treasure map. Tom and Jerry don't know the map is a fake.
Trouble ensues when Tom is separated from his own shadow. Having been strapped with Tom its entire life, the talking shadow refuses to go back to the life he once had!
After the witches fly off into the night, Tom chases Jerry into a room full of enchanted bottles. When Jerry tries to hide in one, he inadvertently releases a mischievous thousand year-old Genie who grants Jerry three wishes.
After an unsuccessful attempt on Tom's part to catch Jerry, a traveling cat salesman is happy to sell Tom just what he needs; a series of elaborate mousetraps, tricks, and schemes. Tom attempts to dish out a world of hurt to Jerry.
Over Ginger's objections, Rick has installed a high-tech home automation system. Tom and Jerry try using the system against each other but eventually the house kicks their butts and they lose complete control of the system.
A cat and mouse ends with Tom taking a shot to the kisser that knocks the cat out. With first aid, Tom awakens a kung-fu master. Now Jerry, Tuffy and Spike must reverse whatever happened to Tom to make him so lethal.
Hildie is mixing a batch of foot balm that'll soften and beautify her gnarly-looking feet. She has Tom rub it in. Unfortunately, the foot balm is a little too strong and makes her foot disappear.
Tyke has some trouble with a plank of wood. Tom tries to remember all the events that occurred while he solved a case in his detective work. Jerry finds himself alone in an empty house.
Pecos pays a visit to Jerry's house and uses Tom as his rodeo horse. When Jerry overhears Rick and Ginger wanting to get rid of a "useless cat", he tries to keep Tom working as fully as possible. Spike realizes he hasn't been the best role model and employs the help of Tom and Jerry to teach Tyke how to be a better loser.
Tom and Jerry make a battlefield indoors. Tom uses the witch's magic wand to give life to a puppet who ends up comparing Jerry to a baby. Spike gets fat by eating too much grilled meat, so Tom and Jerry try to hide all of it so he can't eat any more.
Little Quacker asks for help from detectives Tom and Jerry to help him find his girlfriend, Fifi. Tom and Jerry help Toodles with a dance contest. Tom tries to eat Little Quacker, and Jerry does everything to ensure his protection.
Jerry makes fun of Tom when he starts losing his hair; Detectives Tom and Jerry investigate the case of a mysterious maniacal dog that is astounding every cat in town; Tom becomes a joke when he's forced to use a cone for a week.
Tom and Jerry fight in a museum of national antiques. Sleep-deprived detectives Tom and Jerry try to stop a thief kitten who has been stealing people's personal possessions. Winston runs a small school and Tom and Jerry help him with the most difficult tasks.
Butch finds a wish bone in the garbage and dupes Tom into believing it will make his wishes come true. Butch trades Tom the bone for cans of cat food. Butch thinks he's pulled off the best scam ever until his wishes start coming true.
Tom is ridiculed by everyone when his hilarious video is posted on the internet. Detectives Tom and Jerry try to stop a cheeky tortoise who will participate in a race with his rival, a rabbit. Tom and Jerry face the witches' pet piranha.