Newly engaged Mindy returns from her volunteer mission in Haiti to New York for emergency surgery, only to find a new doctor has taken her place. Meanwhile, Danny and Christina's relationship continues to deteriorate.
Mindy struggles to cope with Casey's new career choice. While most of the hospital staff attend a music festival, a new doctor comes to the rescue as Jeremy and Tamra struggle to cope with the workload.
Morgan sues Mindy for sexual harassment after she backs out of testing his theory that whoever sleeps with him finds the love of their life immediately afterwards. Danny wants Peter out of the practice.
Mindy begins dating an Arts and Culture writer, however when he discerns that she is not cultured enough for him, she decides to invite him to Christina's art show, which features nude photos of Danny.
When Danny tells Mindy she is too picky and judgemental of other people, she tries to prove him wrong by going on a date with her complete opposite. Jeremy is distressed when his dad visits the practice and takes an interest in Peter.
When Mindy tells Danny about a crush on someone in their building, he becomes convinced she is talking about him. Meanwhile, Morgan and Peter find Mindy's missing purse and use her phone to engage in a raunchy text conversation with Cliff.
When one of Danny's patients paints the hospital in a racist light on her blog, Jeremy hires a PR guru to control the situation. Meanwhile, Morgan seeks Cliff's forgiveness for not deleting the raunchy texts sent to Mindy.
Mindy plans a Christmas party for the entire building so she can spend more time with Cliff, however, Brendan's date Maria Menounos steals Mindy's thunder by performing a seductive "Santa Baby" dance for the party guests.
With Danny as her fitness coach, Mindy attempts to get in shape for a weekend getaway with Cliff. Meanwhile, an ill Jeremy takes some time off work and leaves Peter in charge.
Jeremy sends Mindy, Danny, Peter and Morgan to Los Angeles to receive cosmetic injectables certification. Once there, Danny becomes concerned about running into his father, and Mindy runs into her ex-fiance, Casey.
Following their breakup, Mindy is determined to return to New York to win Cliff back, however Danny tricks her into accompanying him to meet his estranged father. Meanwhile, Peter and Morgan get stuck in the bathroom at the hospital.
Mindy and Danny confront the consequences of their kiss. Meanwhile, Jeremy and Peter devise a plan to poach patients from a competing practice that has shut down. Then, Mindy discovers an incriminating video of herself that is floating around the internet, and she enlists the help of Peter to keep it from falling into the wrong hands. Part 2 of 2.
Mindy and Danny try their hand at dating. But they discover that redefining their relationship isn't as easy as they thought it would be, especially when the pharmaceuticals representative (guest star Jenna Dewan-Tatum) whom Danny used to date re-enters the picture. Then, a high-profile doctor (guest star Anna Gunn) and Mindy's idol, tries to poach her. Part 1 of 2.
Mindy and Danny move on. Mindy forms a girl crush on an Obgyn to the stars. The doctors from Shulman's Women's Health Associates head to an under-served community to offer free check-ups.
Peter encourages Mindy to think more like a man. To test his advice, they head out to a bar, where they meet Lee (guest star Max Greenfield), a smooth-talking first-grade teacher who is up to no good. Meanwhile, Danny tries to give relationship advice to Tamra.
Mindy has a run-in with the law when a surly police officer (guest star Tim Daly) admonishes her for giving his young daughter birth control pills. Meanwhile, Danny befriends a rabbi who offers to refer his congregation to Schulman & Associates because he thinks Danny is Jewish.
Danny offers Mindy the opportunity to buy the other condo he owns in his building, but gets jealous when she begins to date Charlie, the police officer (guest star Tim Daly). Meanwhile, Peter dates a brain surgeon (guest star Tracey Wigfield) whom he fears may be too mature for him.
After exchanging a flirty stare with a gorgeous guy in the subway, Mindy is full of joy knowing the guy is actually looking for her by describing Mindy's appearances in the newspaper. Out of plain curiosity, Mindy tries to contact the guy and turns out that he asks her out on a date. Everyone at the office freaks out and starts warning Mindy.