Sheena meets a man who is an Interpol agent who is being hunted by people who want him dead. So she takes him through the jungle. And she takes a personal interest in him. Cutter learns about him and tries to find them so he can help them.
A woman asks Cutter to take her into the jungle because she's looking for a boy who went missing after the plane which he was on with his family went down. They go in his helicopter and someone shoots them down. Later they meet Sheena and she tells them that the boy is heir to a fortune. His father helped her so she tries to repay him by finding his son. She reveals that a relative of his, who could inherit the fortune if the boy is dead, and his business partner are the ones who shot them down.
During an outbreak of a mysterious disease, Sheena and Matt investigate reports of UFO sightings, alien abductions and cattle mutilations. The famous X-Files music sting plays several times throughout the story.
Unaware of the civil war in the area, Cutter drops off a group of inept rich survivalist celebrities in the middle of a jungle to compete for 5 million dollars. Among them are Cutter's NFL idol and a writer whom Sheena met as a child.
Princess of an African tribe arrives from America to marry the prince of a rival tribe and ensure peace between them. Unfortunately, she's become too Americanized, in a bad way, and her jealous stepsister plans to usurp her place.
To gain legitimacy, a usurper needs the holy book of his tribe. Due to a misunderstanding, Mendelsohn becomes their new king instead. Cutter must protect him from the usurper until Sheena and the rightful heir can return with the book.