While in Argentina attempting to exchange a spy, an assassin attacks Annie and the spy, Carlo Reni. Forced on the run, Annie and Carlo have to evade arrest and figure out who set them up before the assassin can catch up with them.
While Annie tries to find out who is giving NASA secrets to the Colombians, Auggie accepts his promotion, and his replacement has difficulty fitting in.
Eco-terrorists hold a group of oil executives hostage in Mexico City, and Ben Mercer re-emerges as part of Annie's team sent in to assess the situation.
Annie discovers that the latest CIA casualty is her former language professor - whom she had no idea was part of the agency - and she is assigned to find a secret message in his documents before his killers.
Annie is tasked with helping a Chinese scientist to defect. Meanwhile, she continues having difficulty fitting in time with Dr. Scott, while agonizing over whether to read Danielle in on her real job, but will circumstances force her hand?
While Annie searches for a new safe house, she is assigned to surveillance duties on a pair of brothers who may be plotting an attack against the Spanish government. Meanwhile, Jai launches a power play to get away from Arthur.
When one of Arthur's former female Cold War assets emerges during one of Annie's missions, he immediately flies to Berlin to help, which sparks Joan's curiosity about their past relationship.
Arthur suspects that an imprisoned spy who betrayed the U.S. may have gotten a Russian asset killed, which leads Annie to a mission to investigate his two daughters, which hits close to home because of her situation with Danielle.
An agent for the British intelligence, MI6, approaches Annie since she is an employee of the Smithsonian. He wants her to help with the surveillance of an art dealer. Kenneth wants her to get him into the Smithsonian to gather information.
An assignment in Stockholm put Annie and Danielle in jeopardy during their vacation, and Jai must choose between loyalties to his father and Arthur after a failed lie detector test.
