Shaun Murphy, a young surgeon with autism and Savant syndrome, is recruited into the surgical unit of a prestigious hospital.
Dr. Oliver Wolf, a gifted neurologist, applies his unconventional approach to treating puzzling psychological cases.
A new medical director breaks the rules to heal the system at America's oldest public hospital.
A young man suffers from an incurable chronic illness known as CIPA which strips the afflicted of their ability to feel or sense pain.
Young doctors Steven and Jerry are rivals professionally and for Paula Norland. Jerry lets Steven take the blame for a mistake he made and sends him to prison. After his release, Steven gets redemption during a storm at sea.
The city's most highly skilled medical team saves lives, while navigating their unique interpersonal relationships.