Insurrection is in the air in 1830's Scotland with both Neil and Dr. Campbell's Uncle Andrew involved. The life of Duncan Sinclair is saved by chloroform, something new tried by the doctor but viewed with suspicion.
Jean changes the dressings on Duncan's leg causing him to develop septicemia. Dr. Campbell is blamed. The villagers no longer listen to Dr. Campbell's medical advice, instead following Jean's folk medicine. Dr. Campbell decides to emigrate.
The Campbells arrive in Canada and enjoy dinner at Logan's Inn with innkeeper, Gabrielle Leger, who warns them that their neighbor, Captain Sims, wants their property. Someone is playing dangerous tricks with near fatal consequences.
Emma and John play pranks to scare away Mary McTavish, their superstitious housekeeper who believes in ghosts and is critical of Emma's homemaking skills. They convince neighbor Richard Sims to impersonate a late-night ghostly visitor.
While hunting, Neil befriends a woodsman who says he will teach Neil to hunt. When he is injured, Neil brings him to the family cabin for medical treatment. When Dr. Campbell discovers he is wanted for murder, he takes the family hostage.
While John and Emma are playing by a stream in the woods, Emma appears to be stabbed and carried off by an Iroquois woman. Dr. Campbell, John and Neil, with the help of Gabrielle Leger, investigate.
Dr. Campbell treats Lady Caroline, an English noblewoman who sprains her ankle while fleeing the man she arranged to marry through transatlantic correspondence.
Dr. Campbell treats a dying man who sailed with the pirate Jean Lafitte. He gives Dr. Campbell a model ship. Meanwhile the patient's housekeeper and her ex-convict brother are searching for his treasure.
Emma grows attached to a gray horse with a black star on her forehead which was given to her father as payment from a patient. Meanwhile an unpleasant stranger is looking for a horse of a similar description who he says was stolen from him.
Dr. Campbell receives a pig as payment for his services. The pig keeps escaping from her pen so Captain Sims tries to claim her when she wanders into his barn.
Dr. Campbell and Captain Sims are concerned that a neighbor's cattle have a highly contagious deadly disease called "murrain" that will spread to the other cows in the community.
As winter approaches, Dr. Campbell experiences financial difficulties when all his patients pay him with pumpkins instead of cash. He considers selling the farm and moving the family to York to practice medicine in the city.
The Campbells are required to clear half an acre of their land in less than a week or lose their property. Captain Sims is the Tory candidate for their district election.
Captain Sims and Dr. Campbell go on a hunting trip to stock up on venison for the winter, but they are captured by a man and his severely injured companion who have deserted the Royal Navy after being impressed into service.
