Skin examines the relationship between artist Ex de Medici, equally renowned for her vivid paintings as for her groundbreaking tattooing, and Geoff Ostling, an overweight 65-year-old whose body has been etched with a tapestry of flowers by Ex's needles and ink. The film charts their journey as Geoff's body suit - their collaborative artwork - is completed after 25 years. Now entirely tattooed, Geoff is forced to confront his mortality as he and Ex undertake to have Geoff's skin preserved and exhibited after he dies.