In 1916 Shanghai, Mei Li marries into the Tian family to protect her brother, managing their pharmacy. After tragic losses, she opens her own drug store while facing opposition to her desires and a catastrophic police raid.

Adapted from the Jinjiang Stone and Water novel "The Career Man". In 1916, Chu Shaohua married Chen Dashun, the eldest son of Chenji Pharmacy, to save her brother Chu Shaozhong. She was appreciated by Chen's father for her integrity and outstanding business skills and became the manager of the pharmacy. After Chen's father and Chen Dashun died unexpectedly, Chen Ershun inherited the drug store and lost all his family wealth. The drug store was in dire straits. With hard work, Chu Shaohua opened Huashun Drug Store to support his family. Chu Shaohua decided to start a new life with his first love Xia Chu, but was blocked by Chen Ershun and Chen's mother. The Chen family was ransacked by bandits, and Chu Shaohua also lost her daughter in this disaster. She was so sad that she left Shanghai alone. Chu Shaohua has outstanding performance in Shanghai Yongxin Department Store. She is invited by the business wizard Wen Zhiqiu to start a business together, and gradually grows into a bold and trustworthy businesswoman.