When violent conflict breaks out between greedy railroaders and a tribe of Mescalero Apaches, only two men, destined to be blood brothers, can prevent all-out war: chief's son Winnetou and German engineer Old Shatterhand.

The construction of the Great Western Railroad creates heavy conflict between the railway company and neighboring Indian tribes. Worse, criminal gang leader Santer sets his eyes on a gold mine located on holy Indian land and influences the construction supervisor to re-rout the planned railroad straight through Apache land. Old Shatterhand, who works as a measurement technician, discovers the evil plan and searches contact with the Apaches in an effort to avert war.—MCSmarties