After defeating Dracula, Van Helsing is granted immortality by the church to pursue and eradicate vampires from the face of the earth. His hunt leads him to a bloody showdown between his slayers and an army of demons.
1885 Transylvania(?): Abraham Van Helsing [Rhett Giles] eaves his wife in thecare of Monk Sebastien [Andreas Beckett] while he and his slayers penetrate the lair of CountVladimir Dracula. Although Van Helsing successfully destroys Dracula, the costis great. The monk Sebastien is actually a vampire prince, and while VanHelsing is out killing vampires, Sebastien turns Van Helsing's wife into one.
Present day Los Angeles: Dr Abraham Van Helsing, slayer of vampires, islaying low, working as a hematologist at University Hospital after just movingthere from Paris. Vampires have been lying low, too, drinking the cold blood ofdead animals, not hunting humans, basically starving themselves all on accountof their fear of Van Helsing. Roman [Jared Cohn] can't take it anymore. He getsa job at University Hospital as anorderly and steals three pints of blood from the blood bank. When Arianna [Denise Boutte],chief vampire bitch, sees the name on the label -- Dr Abraham Van Helsing --she begins to shiver in her black, high-heeled, lace-up boots and runs straightto Sebastien (after taking a few swigs of the blood herself). She offers theblood to Sebastien, who has disintegrated into a withered, sniffling, lustlessragtag lying on a couch and talking in word salad. Arianna forces a sip of thehuman blood down his throat and, after that one sip, Sebastien knows what hemust do -- unite all the vampires, feed again on humans, show them who's boss,and kill Van Helsing. However, killing Van Helsing isn't going to be easy. After being forcedto destroy his own wife, Van Helsing turned to the Knights Templar and made adeal with God. Until he kills the last vampire prince, Van Helsing will walkthe earth as an immortal. The only stipulation is that, should he ever drinkvampire blood, he will be turned and forever damned.
The first thing Sebastien does, now that he's found purpose again, is todrink the blood of a prostitute, banging his chest after the first few swigsand roaring like King Kong. The next thing he does is change into black leatherpants and a new goth shirt and hold a pep rally, inspiring the vampires to comeout from the derelict, stinking, moldering buildings in which they are hidingand rise again as hunters of human blood. As luck would have it, the prostituteshows up at University Hospital, practically drained of blood. She is giveneight units of blood, but she's not getting any better. When nurse Emily [Brent Falco] tellsVan Helsing about the patient, he runs to her room to take a look. Right away,Van Helsing knows that she is changing into a vampire. When no one is looking,Van Helsing sprinkles her with holy water, smothers her with a pillow, drives astake through her chest, and cuts out her heart with a cast saw.
Van Helsing concludes that the vampires are hunting humans again and thatit is time for him to come out of hiding and put together a team of slayers.So, Van Helsing consults Father Cefalu [Anthony Turk], who agrees to find some young,able-bodied, seminary students for him to train. The next morning, Van Helsingmeets seven recruits and gives them a pep talk on the art of vampire slaying.As Van Helsing educates the recruits in the way of the vampire, nurse Emilyshows up. She explains that she works with the homeless at the parish and thatFather Cefalu asked her to come.Suddenly a call comes in. The detective brother of one of the recruits calls to tell him about a body that was just found. It was drained ofblood and its heart was cut out. Van Helsing, Dominic [James Ashby], and another recruit headover to the crime scene and begin their first vampire hunt. They look through anearby abandoned building and, sure enough, there's a coffin with a vampire init. Van Helsing tops the coffin with a branch of wild rose and begins firingbullets into the coffin. On his 11th shot, the group is suddenly set upon by asecond vampire, and the fun begins.
Meanwhile, Roman has learned that nurse Emily is Van Helsing's girlfriend, so he and Arianna wait in the hall for Emily to showup. When Emily appears, Arianna has Roman bite her in the neck, then she fallsinto Emily's arms begging for help. Emily takes Arianna, not to the emergencyroom, but to the church where the slayers are training, also not noticing thatthey're being followed by a slug of vampires. Suddenly, the vampires crash thechurch and start beating up the slayers. When Van Helsing shows up holding across, all the vampires disappear, taking Emily with them. Unfortunately forRoman, he gets left behind [Roman is a bit retarded]. Van Helsing forces Romanto reveal that the vampires have taken Emily to.an abandoned warehousewhere Sebastien is toyingwith her, waiting for Van Helsing to show up. When Sebastien leaves Emily inthe care of another vampire, Emily loosens the bonds around her wrists andsuddenly springs forward, crucifix in hand. The vampire backs away, and Emilythen drinks a bottle of blessed Evian. Meanwhile, Sebastien is rallying hisvampires again. "We are vampires! Yeah! We are hunters! Yeah!" While thevampires cheer for themselves, Van Helsing and his slayers are sneaking up onthem. Suddenly they burst into the warehouse, and it's every vampire and slayerfor himself. Van Helsing goes looking for Sebastian and Emily.
Now comes the big showdown. Sebastien has changed into a bolero jacketwith red tails and cumberband. He and Van Helsing circle each other, makingsmall talk about the past. Off comes the Bolero jacket, revealing a white,gauzy, long-sleeved shirt open to his waist. Van Helsing charges with stakes inhand, but, even after all those years of living on cold rat blood, Sebastien isdefinitely the better fighter. Van Helsing winds up on the ground withSebastien's foot on his stomach. Suddenly, Arianna takes this time to confrontSebastien with his womanizing and let him know how much it hurts her. Afterreminding Arianna who is the master, Sebastien slakes his thirst on Emily. He'sfeeling pretty good about himself until he suddenly gets a tummyache andrealizes that Emily's blood contains holy Evian. Sebastien pounces on VanHelsing anyway, but Van Helsing is able to run a stake through Sebastien'sheart. He then garrots Sebastian's head off his shoulders. Arianna gets stabbedin the stomach but manages to get away.
Now that Van Helsing has killed the last vampire prince, he prepares todie, just as the deal was laid out. When it doesn't happen, he is puzzled. Doesit mean that God has rewarded him with the ability to live out the rest of hislife or does it mean that there is another vampire prince(ss) out there? [Originalsynopsis by bj_kuehl]
