A new epidemic has spread in the near future. The young people struggle to confess their unrequited love in a world where they can speak various languages only if they buy a very expensive cure.

Babel Syndrome depicts the stories of various people who lost their spoken language due to an epidemic that spread a deadly virus, which causes genetic modification. Ha Neul, a young student who dreams to become a poet one day. He has a pure, kind heart who longs for his first love. His perspective about the world changes after he learns the darkest secrets hidden by the society during the deadly epidemic.