The Zodiac Murders series does not aspire to rank among other popular crime serials; it seeks to become one of a new, modern style. The line connecting all its parts are the signs of the zodiac. Each of the twelve episodes deals with a mysterious crime, of characteristics associated with the respective sign. Apart from the standard crime investigation elements, in each episode we can follow a "private" line, represented by an amorous triangle kept secret, formed by major Holina, the intelligent and competent head of the investigation team, his subordinate captain Rostia Bor, confined to wheelchair due to an accident, and his wife, psychologist Sabina, who studies and uses astrology for psychological personality analysis, thus helping the two detectives in their work.