West Texas. A boy who, after his sister is kidnapped by a violent killer known only as Cut Throat Bill, enlists a fierce bounty hunter named Reginald Jones who becomes the leader of the group of outcasts searching for the stolen girl.

When fierce bounty hunter Reginald Jones (Peter Dinklage) is recruited by a desperate man to track down a ruthless killer known only as Cutthroat Bill (Juliette Lewis), he rallies a band of unlikely heroes including a grave-digging ex-slave and a street-smart woman-for-hire. Together they embark on a perilous quest to track down Cutthroat Bill that leads them into the deadly "no-man's-land" known as... The Thicket.