After Peter Parker is bitten by a genetically altered spider, he gains newfound, spider-like powers and ventures out to save the city from the machinations of a mysterious reptilian foe.
Peter Parker (Garfield) is an outcast high schooler who was abandoned by his parents as a boy, leaving him to be raised by his Uncle Ben (Sheen) and Aunt May (Field). Like most teenagers, Peter is trying to figure out who he is and how he got to be the person he is today. Peter is also finding his way with his first high school crush, Gwen Stacy (Stone), and together, they struggle with love, commitment, and secrets. As Peter discovers a mysterious briefcase that belonged to his father, he begins a quest to understand his parents' disappearance - leading him directly to Oscorp and the lab of Dr. Curt Connors (Ifans), his father's former partner. As Spider-Man is set on a collision course with Connors' alter-ego, The Lizard, Peter will make life-altering choices to use his powers and shape his destiny to become a hero.—Columbia Pictures
The Amazing Spider-Man follows the origin story of Peter Parker's beginnings as the world-renowned wall-crawler. After being bitten by a radio-active spider, Peter acquires amazing abilities which will help him achieve things one could only dream about. In a life-threatening fight for the city, Peter will strive to protect New York City from the threat of his friend-turned-enemy, Doctor Curt Connors: whom has transformed into The Lizard.—Johnny
Spending his days trying to unravel the mystery of his past and win the heart of his high-school crush, Gwen Stacy, bookish teenage social outcast Peter Parker has a lot on his plate already. Reared by understanding Uncle Ben and loving Aunt May, Peter accidentally finds a hidden briefcase: a mysterious discovery that leads to an extraordinary transformation and a new identity. However, as Peter embarks on a painful mission to find answers and an unstoppable reptilian adversary threatens the metropolis, the agile web-spinning hero must summon up the strength to defend his beloved New York City. Will Peter follow the arduous path of responsibility? Can the amazing Spider-Man save the city from Lizard, the monstrous mega-villain?—Nick Riganas
Peter Parker is a seventeen year old high school student at Midtown High, he has a secret crush on Gwen Stacy and he is constantly bullied by Flash Thompson. Peter's life has changed greatly for him, ever since his parents left him when he was only four years old and he has been placed under his aunt and uncle's care for about thirteen years. Peter still wants to learn more about his past and he wants to know why his parents left him. Peter finds his father's briefcase and he learns that his father has worked at Oscorp with Dr. Curtis Connors, a brilliant scientist and herpetologist. Peter becomes determined to find answers from his father's former partner. However, Peter's life soon changes when he is bitten by a spider during his trip to Oscorp and he is granted spider-like powers. Peter soon witnesses his uncle's murder at the hands of a shoplifter and he vows to use his powers for the greater good and he names himself Spider-Man. Peter's newfound friendship with Connors will be put to the test when he must fight the Lizard, Connors' deadly alter-ego who plans on infecting the city.—dawsonpersi
Young Peter Parker discovers his father's home office has been ransacked. His parents, Richard and Mary Parker, hurriedly gather secret documents, leave Peter with his Aunt May and Uncle Ben, and disappear under mysterious circumstances.
Years later, teenage Peter attends Midtown Science High School, where he struggles with social awkwardness and bullying. Despite this, he harbors a crush on Gwen Stacy, who reciprocates his feelings. While searching through his father's old briefcase, Peter discovers clues linking his father to Dr. Curt Connors, a scientist at Oscorp specializing in cross-species genetics.
Peter sneaks into Oscorp, where he encounters a lab housing genetically engineered spiders. One of the spiders bites him, granting him spider-like abilities, including enhanced strength, agility, speed, sharp senses, and the ability to cling to walls. Meanwhile, Connors, whose right arm is amputated, is working on experiments to regenerate limbs using lizard DNA.
Peter finds the missing element in his father's research-the "decay rate algorithm"-and shares it with Connors, revealing his connection to Richard Parker. As Peter begins to explore his powers, tensions rise at home. After a heated argument with his Uncle Ben, Peter storms out. While searching for Peter, Ben intervenes in a robbery attempt, is shot by the thief, and dies in Peter's arms. Consumed by guilt, Peter dedicates himself to tracking down criminals matching the killer's description. To conceal his identity, he designs a suit, dons a mask, and constructs mechanical web-shooters.
During a dinner with Gwen's family, Peter learns that her father, police captain George Stacy, views the masked vigilante Spider-Man as a dangerous menace. Peter later reveals his secret identity to Gwen, deepening their bond.
Connors, pressured by Oscorp executive Rajit Ratha to begin human trials, refuses to endanger innocent lives. Fired from Oscorp, Connors tests the serum on himself. The serum regenerates his missing arm but mutates him into a monstrous humanoid reptile, the Lizard. Connors, now fully transformed, attacks Ratha on the Williamsburg Bridge, putting civilians at risk. Peter, as Spider-Man, intervenes, saving the bystanders but drawing the attention of the police, who begin a manhunt for both Spider-Man and the Lizard.
Peter tracks the Lizard to the sewers, where Connors discovers Peter's identity from a camera left behind with Peter's name on it. Connors retaliates by attacking Peter at his school, leading to a chaotic battle. Peter learns that Connors plans to release a biochemical agent from Oscorp Tower to transform New York's population into reptilian hybrids, aiming to eliminate humanity's weaknesses.
Captain Stacy and his officers corner Spider-Man, but Stacy uncovers Peter's identity and releases him to stop Connors. Gwen creates an antidote to reverse the mutation, which Peter disperses through Oscorp's ventilation system. The city's residents, including Connors, are cured, but not before the Lizard fatally wounds Captain Stacy.
In his dying moments, Captain Stacy asks Peter to keep Gwen safe by staying away from her. Heartbroken, Peter agrees. However, both Peter and Gwen struggle with their separation, and Peter hints that he may not keep his promise.
In a post-credits scene, an imprisoned Connors is confronted by a shadowy figure who inquires whether Peter knows the truth about his father. Connors insists that Peter remains unaware and demands that he be left alone. The mysterious figure disappears, leaving Connors unsettled.
