Returning to the medical school where they were test subjects decades ago, a pair of outrageously twisted serial killers use shockingly brutal sex acts to start killing off a group of drugged-out med students.

The shocking news of the gruesome, sex-related homicide of medical student, Ray Harris, spreads like wildfire in the Linda Vista Community Hospital. Was it a deviant S&M game gone wrong or is there, indeed, a deranged serial killer lurking in the campus? As the police investigation continues, a strange connection between the highly experimental hallucinogen, Taldon, and the peculiar 1973 case of John and Wilma Hopper emerges, while Ray's friends, start being stalked by a pair of insane sociopaths who have only one intention: to ravish them to death. And, before long, warm, bright-red blood will flow. Is there an escape when the enemy lives inside one's head?—Nick Riganas

In this genre-defying grind-house throwback, a group of drug-addled, sexually deviant medical students are systematically terrorized by Wilma and John Hopper. The Hoppers, serial murderers and rapists, mysteriously return from the 1970s, and bring horrifying psychedelia with them. With comedy, subversion, satire and true gore, the students must face escalating attacks, shocking circumstances and visceral disgust.—Anonymous