Bernice and Detty are half-siblings whose bitter rivalry dates back to when they were kids. When their father passed away, things went downhill from there which led to the two siblings never speaking to each other again. That changes when Detty applies to be Bernice's assistant, not knowing that Bernice is her sister.
With a strong lust for vengeance, Totoy/Bernice rises to the top of the fashion industry. He is the illegitimate son of a maid and a rich man (Sambroso) whose wife looks down upon the poor. The wife pushes his mother down the staircase, causing her to be paralyzed from the waist down, and Totoy is left to get her out of the rain and off the streets, and he makes getting revenge on the Sanbrosos his life's goal. He remembers his half-sister Bernadette "Detty" Sambroso, and when he chances upon her at his fashion agency's hiring, he immediately hires her and makes her life miserable. Detty transfers to his rival Roselle's fashion agency, where Roselle plans to kill Detty for rising to the top of the agency and taking her place. Totoy/Bernice gets a change of heart and tries to save Detty and her children from getting shot. The police come, arrest Roselle and her henchmen, and take Totoy/Bernice, Detty, and the children to the hospital, where Totoy/Bernice and Detty reconcile and build a merged fashion agency: Sisterakas.—settesb
The childhoods of Bernice (Vice Ganda) & Detty (Ai-Ai Delas Alas) were world's apart, but they did have one thing in common: their father. Bernice's birth was the result of an infidelity on his behalf, however, and so while Detty grew up with a wealthy family, Bernice and his mother were left to fend for themselves.Years later, Bernice has become a wealthy and successful businessman, the so-called "Lord of Apparels". But his abrasive personality and rudeness has led to the resignation of his 75th assistant. Detty, meanwhile, is in dire need of a job and applies for the newly vacated position as executive assistant to a man that, unbeknownst to her, is actually her half-brother. Bernice knows exactly who she is and hires her. For Detty, this job means she can take care of her daughters; for Bernice, its a chance for payback.Meanwhile, the main rival of Bernices company is currently posing as very strong competition. Headed by the eccentric yet equally brilliant & talented Roselle (Kris Aquino) the competition gets tougher, and a string of events lead to the two company heads fighting over the once expendable Detty.
