Genaro gets a job at a resort in hopes of marrying an American woman and moving to New York in search of a better life. He meets a tourist called Martha and everything seems going according to plan, until her boyfriend shows up.

Sanky Panky tells the story of Genaro (Fausto Mata), a not particularly handsome Dominican mulatto. He works in a colmado - a combination of a store and a bar - in the slum of El Capotillo in Santo Domingo. The opening scene focuses on Genaro, who is trying with great difficulty to learn English. He is preparing to make his big dream of going to the United States with an old gringa come true. The traits of such women are later defined by his friend Carlitos as "flabby, cellulite, boobs, navel, boobs, white like milk." Genaro manages to find work at a family resort due to his friendship with its Italian manager Giuseppe (Massimo Borghetti). The fact that he has to dress up as a chicken to entertain the children does not prevent him from trying his luck with the women. Surprisingly, he manages to charm Martha (Zdenka Kalina), a young American who, in order to forget her boyfriend spending a week in the Dominican Republic in the company of her two aunts, Helen and Dorothy . To win Martha over, Genaro enlists the help of his two friends, Chelo (Tony Pascual) and Carlitos (Aquiles Correa), who meanwhile have turned the colmado into an open nightclub, despite Genaro having banned music being played during his absence of him. Chelo and Carlitos entertain the aunts, whose sexual fantasies they try to satisfy, while Genaro sets about seducing Martha. In the end, Martha's boyfriend Alex (Miguel López) arrives, and after some complications Martha leaves, while the two friends accompany the gringas to the United States and Genaro stays with La Morena (Alina Vargas), a Dominican who has also been making a living in the resort and with whom Genaro has shared his woes.—Premium Latin Films