A college student creates a drug called "Z" and sells it on campus, inadvertently resurrecting the living dead, who wreak havoc at a Halloween rave.

While illegally selling one canister of Trioxyin-5, Charlie Garrison is murdered by a zombie. His nephew Julian Garrison finds two canisters hidden in the attic of his house with his girlfriend Jenny and they ask their friend Cody to analyze and research the chemical product. Cody finds that the composition of the product is very similar to ecstasy and he processes the chemical, making a large quantity of a drug that he called "Z" to make money. Using the services of the local drug dealer, they sell "Z" in the college campus. In the Halloween, the DJ and Jenny's brother Jeremy organizes a rave party. Meanwhile, Julian, Jenny and Cody disclose that the drug transform the users in zombies, and with the support of two weird agents, they try to stop the distribution of "Z".—Claudio Carvalho, Rio de Janeiro, Brazil

Julian and his few friends that actually managed to escape Necropolis have all enrolled in college and are trying to put their experiences with Hybratech behind them forever. Soon after, Jenny and Julian find a strange chemical container in a hidden room. In an effort to find out what this chemical, labeled as Trioxyin-5 is, they take it to their friend Cody for screening. However, Cody soon finds a way to make party drugs from it and try to earn some quick cash. Cody then makes a huge quantity of a drug called 'Z' that he begins to sell to the college kids. Soon, Halloween approaches, and almost all of the college kids have already taken 'Z'. After the drug takes effect and turns the kids into zombies, the Halloween costumes everyone is wearing make it hard to distinguish the living from the undead.—Guy