A desperate wife agrees to have a baby cloned from her comatose husband's DNA. However, the husband gets better and they get rid of the baby - until the past comes calling decades later in a mix of mystery, lust and violence.

Josie, a devoted wife, is devastated when her beloved husband, Leo, falls into a coma after a terrible accident. Desperate to have his child, she accepts her only option: cloning. The arrival of the baby unexpectedly awakens Leo, unleashing in him a newfound ability to experience supernatural visions. These visions weaken him and reveal a terrible, cursed future which he cannot understand or accept. Confused and intensely anxious by what she's done, Josie tries to deny what she's created, but her husband's reactions grow stronger to the baby. She confronts the doctor who spearheaded the experiment fearful that the man and his clone cannot coexist - but the baby is too great a danger. Leo and Josie are forced to make an impossible choice and keep a secret forever. The couple remain together, their love continuing, his career thriving. But twenty years later their past comes back to haunt them. The truth cannot be buried. Patient 001 is a dark, twisted, Gothic fairy tale for grown ups.