A Japanese scientist accidentally releases a giant monster in the U.S., and must save it-and Cincinnati-before a crazed nuclear physicist destroys both.

Japanese forces destroy a giant monsters as a young paleontologist rescues the offspring, whisking the mysterious red egg off to safety in friendly Cincinnati, Ohio (Ohio means "hello" in Japanese). However, as the jet arrives, he accidentally flushes the egg down the toilet. It disappears into the Ohio River just as a group of physicists, led by the brilliant (or maybe not) Dr. Richard Blowheart, are testing "uber-fission" power at SNUGI, the Secret Nuclear Underground Government Installation 500 stories beneath the city of Cincinnati. Shaken loose by testing, the egg is quickly discovered by Blowheart and his assistant, Dr. Shirley Yujest. The two soon meet professor who tells them that the egg contains a living Notzillasaurus Partiontilldon. The creature will remain small, he explains, as long as it is not exposed to alcohol.