In order to resist temptation, Mariana and her girlfriends try their best to control everything and everyone around them. However, the day will come when the urge to scream will be stronger than it ever has been.

Mari and her friends broadcast their spiritual devotion through pastel pinks and catchy evangelical songs about purity and perfection, but underneath it all they harbor a deep rage. By day they hide behind their manicured facade, and by night they form a masked, vigilante girl gang, prowling the streets in search of sinners who have deviated from the rightful path. After an attack goes wrong, leaving Mari scarred and unemployed, her view of community, religion, and her peers begin to shift. Nightmares of repressed desires and haunting visions of alluring temptation become undeniable and the urge to scream and release her paralyzing inner demons is more powerful than ever before. A neon-tinged genre-bender that gives provocative form to the overwhelming feminine fury coursing through modern life, MEDUSA dares us not to look away.—Music Box Films