Queens tells the story of women survivors of a crime family's multiple murder. They struggle to reclaim their lives and status, fighting against other mafia families bent on destroying them and taking their business and wealth.

In the midst of the bachelor party of Eyal Malka, one of the largest crime families in Israel, assassins kill all the men and "soldiers" of the family, led by Jacob Malka, the father of the family. The women of the Malka family, who have lost their status and power all at once, are thrown into a new reality in which they must fight for their place in the male world of the temple only power. The series tells the story of the family wives who try to stand on their feet again and rehabilitate the family business taken from them, as well as avenge the deaths of their loved ones.