Louis Theroux visits three American cities and examines a uniquely devastating human crisis in each - opioid and heroin addiction in Huntington, sex trafficking in Houston, and murder in Milwaukee.

BBC2 documentary film maker Louis Theroux investigates the current situations of three US cities which, for varying reasons, have seen their current situations of deprivation intensify in recent years. Theroux analyses the long-lasting negative effects these catalysts of destruction have had on the citizens, the culture and the infastructure of these cities.—jameshammettburke