A Feng Shui Master decides to create a tiger arena in the center of the capital. But a strange virus infects animals and now hundreds of mutant tigers are breaking out into the streets and drowning the city in blood.

During the Ming Dynasty, in order to regain his power, the eunuch Pang Dezhong, who was in power, ordered the establishment of hunting grounds in the small border city of Liangcheng to hunt tigers for refining "Huyuan Jindan", but in the process, the tigers mutated, became manic and painless, and the local tigers were infected one after another. On the other hand, Zhang Liucheng, a hundred families of Jinyiwei, fled to Liangcheng with the rescued Zhongliang after Huan'er, wanting to find his younger brother Zhang Liucheng, who was a hunter in the local area, but encountered hundreds of mutant tigers besieging Liangcheng and wantonly slaughtering the residents of the city.