A young woman discovers her destiny as an heiress of intergalactic nobility and must fight to protect the inhabitants of Earth from an ancient and destructive industry.
Jupiter Jones was born under a night sky, with signs predicting that she was destined for great things. Now grown, Jupiter dreams of the stars but wakes up to the cold reality of a job cleaning other people's houses and an endless run of bad breaks. Only when Caine Wise, a genetically engineered ex-military hunter, arrives on Earth to track her down does Jupiter begin to glimpse the fate that has been waiting for her all along - her genetic signature marks her as next in line for an extraordinary inheritance that could alter the balance of the cosmos.—Production
Earth's residents are unaware that the human species on Earth and countless other planets were established by families of alien royalty for the purpose of harvesting the resulting organisms to produce a type of youth serum for the elites on other planets. After the death of the matriarch of the House of Abrasax, the most powerful of the alien dynasties, her three children Balem, Kalique and Titus are fighting over the primary heir. Jupiter Jones, an unlucky caretaker of other people's houses, is identified as the genetic match of the murdered alien matriarch who used to rule Earth. Genetically engineered ex-military hunter Caine Wise shows up to protect her from alien assassins and take her to outer space, where the heirs of the Abrasax Dynasty are plotting against her.—Warner Bros. Pictures
At the beginning of the story, Earth's residents are unaware that the human species on Earth and countless other planets were established by families of trans-human and alien royalty for the purpose of later "harvesting" the resulting organisms to produce a type of youth serum for the elites on still other planets. After the death of the matriarch of the House of Abrasax, the most powerful of the alien dynasties, her children, Balem (Eddie Redmayne), Kalique (Tuppence Middleton), and Titus (Douglas Booth), quarrel over the inheritance, with Balem inheriting an enormous refinery on Jupiter and Titus declaring his intention to dismantle the youth serum trade, of which Earth is the next intended source. As part of the inheritance Balem has inherited Earth, whose vast source of harvest ready humans make it a more valuable planet than any other in the realm. Titus & Kalique want to stop Balem from having so much power.
Protagonist Jupiter Jones (Mila Kunis) narrates that her father, Maximilian Jones (James D'Arcy), met her mother, Aleksa (Maria Doyle Kennedy), in Saint Petersburg. After Maximilian is killed in a robbery, Aleksa names their daughter Jupiter, after his favorite planet, and they move to Chicago to live with Aleksa's family.
Many years later, Jupiter works with Aleksa and her Aunt Nino (Frog Stone) to clean the homes of wealthy neighbors. To buy a telescope, Jupiter agrees to sell her eggs with the help of her cousin Vladie (Kick Gurry), under the name of her friend Katharine Dunlevy (Vanessa Kirby). At Katharine's house, Jupiter and Katharine are attacked by extraterrestrial 'Keepers'; and when Jupiter photographs these, they erase her memory of the incident. During the egg donation procedure, the doctors and nurses are revealed to be Balem's agents, sent to kill her, and she is saved by Caine Wise (Channing Tatum), a former soldier sent by Titus. Stinger Apini (Sean Bean), an old comrade of Caine's, agrees to help Jupiter. Apini explains that Jupiter is a royal herself. Apini used to serve the Abrasax house, until he lost his wings & was posted to Earth in disgrace. Caine promises to get him his wings back, if he helps Titus. That evening Apini & Caine are attacked by Keepers again, who are intent on killing Jupiter.
But a group of hunters intervene & save Jupiter & take her to Kalique's palace on a distant planet (Caine also gets on board the spaceship without being noticed), where Kalique explains that Jupiter is genetically identical to the dead matriarch (who was murdered), and therefore the Earth's rightful owner. Kalique reveals she is 14,004 years old & her mother was 91,000 years old when she died. It was the youth serum from harvested populations that kept them alive for so long. Supported by Captain Diomika Tsing (Nikki Amuka-Bird) of the Aegis (an intergalactic police force), Caine retrieves her from Kalique, and brings her to the planet Ores (the intergalactic capital planet) to claim her inheritance.
On the way back to Earth, Titus detains Jupiter and Caine (with the help of Stinger, who betrays Caine), to whom he reveals his plan to marry and then kill Jupiter and claim Earth before throwing Caine into the void. To Jupiter, Titus reveals that each unit of the youth serum is extracted from a 100 humans & Earth is just a farm, & one of thousands of planets set up by families such as Abrasax to fulfill an ever-increasing demand for time. Titus says that his mother wanted to stop the trade & hence was murdered & now he wanted to do carry on with her work. He convinces Jupiter to marry her by saying that his life is in danger from Kaligue and Balem & if he dies, he doesn't want his inheritance to go to them, but to someone he trusts would carry on his work.
Caine survives (with some help from Stinger, who has come to his senses) and saves Jupiter at the altar. Jupiter asks to return home but learns that her family has been taken hostage by Balem. In his refinery in the Great Red Spot, Balem demands Earth in exchange for Jupiter's family.
Realizing that Balem can "harvest" Earth only with her permission, Jupiter refuses. Balem tries to kill Jupiter; but she defeats him in a fight, and is rescued by Caine, Stinger, and Tsing while Balem falls to his death. Jupiter's family is returned home with no memory of their disappearance, while Jupiter secretly retains ownership of the Earth. Her family buys her the telescope she wanted, and Caine receives a pair of wings earlier removed from his body. Jupiter also gains the boots like Caine's, and we see them kissing on the rooftop.
During the ending credits it is revealed that the planets that make up the universe form endless DNA patterns showing how vast the harvesting industry is.
