Students and security guards of a flight attendant school in Haixi City work together to survive an attack by a horde of venomous snakes and a mutated giant boa, which have escaped from an illegal breeding base located in the nearby hills.

It is graduation day at a flight attendant college in Haixi City, and many of its students look forward to earning their wings. Meanwhile, the owner of a snakeskin leather factory in the nearby hills on the city's outskirts attempts to attract investors by conducting illegal breeding experiments at its affiliate snake farm by recklessly feeding the serpents with strong hormones, gradually mutating them, with a boa growing into a gigantic size. Threats arise when the mutated snakes attack the investors and escape from the farm, ready to strike the residents of the city. Now, the student body and security team of the flight attendant academy must bond and work together to survive and eliminate the threat.

A group of investors are attracted to a leather manufacturing company located in the hills on the outskirts of Haixi City, where the owners show their ability to produce more snakeskin by feeding the serpents in the factory's partner snake farm with strong hormones. However, the illegal and reckless methods of feeding cause them to mutate and grow aggressive. After a sudden attack leaves the the investors and some proprietors dead, the snakes escape from the farm, posing a threat to the city, terrorizing its residents. The threat eventually reaches the nearby aviation academy, which is celebrating another milestone graduation. As the student body suffers from the terror and are evacuated, the remaining graduating candidates must survive the ordeal by working with the school's security team to eliminate it.