Jackson is a comedy of errors that deals with problems that alcoholism gives rise to, albeit in a humorous manner.

Jackson (Vijay) is in love with his neighbor Kumuda (Vrinda Pavana). But her father Srinivas (Nagendra Shah) has some other plans. He takes help from Annayya (Rangayana Raghu), a mediator, and ask Jackson to stay away from his daughter. Meanwhile, a murder takes place in a bar. Husband of Baby (Deepa) is murdered by Bucket Babu and Rocket Raja. Another twist comes when Jackson loses his cellphone which eventually reaches the villains. An accident brings Jackson to a hospital and that's his moment of glory. He saves the life of a girl by donating blood as requested by Kumuda. That brings the couple together.

This offbeat drama delves into the life of a drunk and a wastrel, whose sole ambition in life is to make a girl he is in love with since his school days, happy. The young woman, however, detests him and takes the help of a gangster and his goons to bash him up to prevent him from following her. Then there is a bank employee, who is trying to juggle a high stress job, a difficult boss, family responsibilities and an extremely demanding and suspicious girlfriend, who is after him to give up his drinking habit. Two criminals planning the murder of a dangerous local don and the brother of the murdered don, desperate to avenge the death of his brother, are all inextricably linked by a murder at the local bar, around which the story revolves. This thrilling saga depicts events taking place on a single day, while several flashbacks, which lead to the present context and give us an insight into the lives of these characters. How will the murder affect each of their lives?—Shrinivas G. Kulkarni