Iron Claw is the leader of a global criminal empire known simply as "Crime". With a network of wealthy and influential sympathizers and employing an army of faceless, leather-masked thugs and cyborg assassins, Crime seeks to become the most powerful mafia organization in the world. To combat this threat, ISSIS, the International Science Special-Investigation Squad, is formed. ISSIS organizes its forces around the world to battle Crime, including Tokyo, Japan. Tokyo's ISSIS
