Despite being in prison, Italy's most wanted gang of academics must stop Walter Mercurio from unleashing a deadly nerve gas on the elite.

A few months since Pietro Zinni's gang got caught in the Sopox production laboratory, each of them is locked up in different jails. From Regina Coeli, Pietro keeps warning the authorities about a synthesized nerve gas and ready to make a killing, but no one takes him seriously. He puts in for a transfer to Rebibbia to meet Murena, who has useful information to intercept the murderer. After which Pietro wants to get the gang of university researchers back together: the perennially unemployed (or detained) most brilliant minds around.—Julia Screti