In this wicked animated comedy, Mel Wax (Michael McKean) is the head of a dysfunctional Hollywood indie movie studio, Hopeless Pictures, so named after his deceased parents, Hope and Les. In the land where a studio chief is only as good as his last big flop, Wax struggles to reign in out-of-control, pill-popping Swedish directors and egomaniacal stars, while coping with a vengeful soon-to-be ex-wife (Lisa Kudrow), assorted affairs, his idiot nephew/head of production (Bob Balaban), a hostile takeover and an inept psychiatrist, Dr. Stein (Jonathan Katz). Jennifer Coolidge plays Hopeless Pictures' head of development, Tracy, as well as actress Nina Boroslova.