Hands of Murder (also known as Hands of Mystery and Hands of Destiny) was an American mystery/anthology series that aired on the DuMont Television Network.; seen on Friday nights.

The show aired from 24 August 1949, to 11 December 1951,[ and was a prime time mystery/anthology series also known as Hands of Destiny and Hands of Mystery. The show, produced by Lawrence Menkin, aired Fridays at 8:00pm ET during the 1949-50 season, Fridays at 9:00pm ET during the 1950-51 season, and Tuesdays at 10:00pm ET during the 1951-52 season.—Paul Gerard Kennedy