Girl of the Night is about Bobbie (Anne Francis), a sensitive, lonely call girl who is manipulated and ultimately used by her madame, played by Kay Medford.

Based on a book by Dr.Harold Greenwald: The Call Girl a Social and Psychoanalytic Study. This film tells the story of a girl (Anne Francis) who becomes a high priced call girl. She is exploited by her madam (Kay Medford) until she finds a tough yet caring therapist (Lloyd Nolan) and straightens herself out.—Anonymous