Five successful women--Georgia, Chloe, Stella, Ina, and Charley--are all having affairs with married men.
Georgia, Stella, and Charley watch a video scandal of a mistress caught by the wife. Charley tells them that she experienced the same scenario and instead watches the movie with her kids at a supermarket to avoid the wife. Stella ends the conversation that she only meets his lover Ambet Villoria at home to avoid any scandal. In a lounge bar, Chloe, the most rebellious mistress is embarrassed by the cancellation of credit card by her lover Gabriel. In anger she throws her phone accidentally not knowing someone was hurt. Stella helps her out of prison but asks her not to tell what happened with the other girls.[7]
Meanwhile, Georgia is tasked by her lover to train a new woman of Frank Ayson, a rich politician and boss of her lover. She reluctantly agrees and meets up with Stella in a coffee shop to get some advice before going to the airport and meet Ina, the new mistress. Ina is ecstatic at first but becomes depressed after learning from Georgia that despite having a condo and a luxurious life, she cannot live with Frank, for whom she left her life in Cebu for. She is even more frustrated by the rules given by Georgia, which includes never calling Frank and never showing herself in front of him unless he asks her to. She ends up depressed as the days pass and overdoses herself on alcohol. Georgia rushes her to the hospital where she meets Chloe.
The next day, Georgia introduce Ina to Stella, Chloe and Charley. The girls start to form a stronger friendship and bond at a mall and a beauty salon using Charley's credit card. Ina meets up with Frank at a Christmas caravan with Chloe's help. Georgia angrily tells Ina that she should not break her rules. Chloe discovers that Gabriel has another mistress.
In Georgia's absence, Ina stays with Charley and accompanies her in an auction but she is caught by Wang Gie's wife and suspended from going out. Ina chooses to stay with Stella in a court room but an accident causes Stella to fly abroad leaving Ina alone. She decides to go back to Cebu to reunite with her family, but is disappointed when she sees that they have learned to live a life without her. This convinces Ina to stay as a mistress.
Ina attends Senator Adelle Ayson's birthday party to get a glimpse of Frank with Chloe's assistance. Georgia is horrified in the meeting of the two and confronts Chloe. The incident separates Chloe from the rest of the group. A news breaks out that Ambet is missing and the mistresses reunite with Stella who is hiding him in a safe house. Prior to the accident, Ambet is diagnosed with cancer and is terminally ill. After a talk with Gabriel's wife, Chloe faces her friends again but nobody is interested to listen to her realization that their lovers will never choose them.
The girls learn that the police found their location through Chloe. Charlie decides to break a rule in order for Stella and Ambet escape using Frank's influence and Wang Gie's plane. Georgia has one more rule for Ina and both of them leave their partners.
Chloe then accepts the job that was offered to her, Stella visits Ambet's grave, Charley returns to the Philippines with her two kids, Georgia marries a guy with twins and Ina becomes a singer and marries a handsome man.