Eight friends, all in stable relationships, venture into a game of sexual discovery by exchanging couples while trying to free themselves from their daily routines and add a spice to their love lives.

El Juego de las Llaves is a half-hour drama-comedy based on the lives of millions of couples with intimacy problems driven by long-term monogamy, self-fulfillment, and desire. The series focuses on the story of four couples, all in stable relationships, who venture into a game of sexual discovery by exchanging spouses while trying to free themselves from their daily routines and spice up their love lives. As each travels through his or her own secret desires, the game takes on a life of its own and the couples must face the impact of their decisions and their own perspectives on sexuality.