Thompson's gang assaults a caravan; Bill, an involuntary witness, manages to escape and save Linda's life. The two take refuge in the neighboring village, that is, where the bandits are.

On his way to the dusty town of Santa Anna to protect Sanders, a man trying to make a deal with the Mexican bandit, El Santo, for the safe passage of his cargo, the solitary gunslinger, Bill, realises that he has arrived at the rendezvous point too late. With Sanders and his entire family murdered, Bill suspects that the deceased's dangerous rival, Dr Thompson, and his henchmen are behind the bloody assault, trying to make a profit from the same deal. Now, Bill is all alone in the town of jackals. Can taciturn Bill outsmart Thompson's men, and get out of Santa Anna in one piece?—Nick Riganas

Django arrives in the town of Santa Anna at the behest of a man named Sanders who'd been trying to buy safe passage for his cargo from a Mexican bandit named El Santo. Django finds that Sanders has been killed and that his rival, a man named Thompson, is now trying to deal with El Santo. Django, after a brief involvement with a beautiful young widow named Linda -- who has information on a lost gold mine -- becomes entangled in this situation by agreeing to escort a shipment through El Santo's territory.—dinky-4 of Minneapolis