The lives of a dozen characters, both good and bad, are interlinked by one common theme - money.

Chithiram Pesuthadi 2 is a movie that depicts the multifaceted nature of any city, here predominantly Chennai. Also, it beautifully brings out the fact that good wins over the evil. Every character in this movie is given an opportunity to choose to do good or bad, at a given situation and depending on their choice, the consequences unfold.