The crew of the spaceship Argosy responds to a distress call from the planet Mara, only to uncover that the industrial world is governed by a malevolent Mother Vampire, setting the stage for an epic confrontation.

In this '60s retro prequel to the bizarro-noir Bloodsucker's Handbook (AKA Enchiridion), Bloodsucker's Planet follows the crew of the space ship Argosy as they respond to a distress signal from the industrial Planet Mara only to discover the planet is ruled by the sinister Mother Vampire. Along the way, they encounter disease-carrying Mara bats, a talking space roach, and Adrianna, the gynoid whose developing self-awareness is aided by her collection of vintage romance comics.