In the future, humanity wages war with giant humanoid weapons called Titanostrides.

In the future, humanity wages war with giant humanoid weapons called Titanostrides. Isami Ao of the Japan Ground Self-Defense Force and Lewis Smith of the United States Marine Corps meet on the battlefield in Oahu, Hawaii. An enemy aircraft attacks, scattering their forces. To survive the battle and save their friends, unlikely comrades must find the courage to defeat this new threat.