The strangled corpse of a pregnant woman turns up in a chunk of ice floating in the Hudson; a man is poisoned to death by a lethal chemical that is almost impossible to obtain. The mysteries surrounding these and other cases might have remained unsolved were it not for the efforts of the forensic pathologist. These 'detectives of death' give the dead the voice they need to reveal who, or what, lead to their ultimate demise.—Anonymous

Autopsy examines how forensic examiners can offer insights into crimes. "The Robert Curley Case" examines the mysterious death of a university electrician who was poisoned with large doses of thallium. "The Collector" looks at a Dallas serial killer who took eyeballs as trophies. "Murder in Paradise" examines how forensic evidence led to the arrest of a Yellowstone Park poacher. "The Roy Kirk Case" looks at the case of a slumlord who murdered a neighbor a neighbor after she filed a complaint. "A Bad Impression" examines how a wad of chewing gum helped to identify two prostitutes that murdered a pimp. "The Videotape Murder" looks at how a video of skaters was used to exonerate a suspect because she was missing her fingertips. "The Mary Ann Powell Case" examines how a scratch on an aluminum seat helped to solve the murder of a pregnant woman.—Shatterdaymorn