The show follows the everyday lives of four high school girls who are all virgins. They go through the ups and downs of adolescence together, including first love, heartbreak, and everything in between.

The romance story centers around Hana Natori, an earnest, good-natured 25-year-old woman whose cousin refuses to go to high school. Hana takes her cousin's place and attends the high school. On her first day, though, Hana's ruse is discovered by her former high school classmate Okito Kanie - who happens to be the high school's world history teacher.