- Spencer Tracy
- Sam Craig
- Katharine Hepburn
- Tess Harding
- Fay Bainter
- Ellen Whitcomb
- Reginald Owen
- Clayton
- Minor Watson
- William J. Harding
- William Bendix
- 'Pinkie' Peters
- Gladys Blake
- Flo Peters
- Dan Tobin
- Gerald Howe
- Roscoe Karns
- Phil Whittaker
- William Tannen
- Ellis
- Ludwig Stössel
- Dr. Lubbeck
- Sara Haden
- Matron
- Edith Evanson
- Alma
- George Kezas
- Chris
- Jimmy Ames
- Cab Driver
- Herbert Ashley
- Stage Doorman
- Dorothy Ates
- Phone Girl
- William Bailey
- Baseball Fan
- Brooks Benedict
- Clayton's Secretary
- John Berkes
- Pal
- Symona Boniface
- Tess' Party Guest
- Elfriede Borodin
- Leni
- Jack Carr
- Baseball Spectator Behind Tess
- Ruth Cherrington
- Foreigner
- Ann Codee
- Madame Sylvia
- Jimmy Conlin
- Reporter at Bar
- Jules Cowles
- Joe the Bartender
- Floyd Criswell
- Policeman
- Fern Emmett
- Justice of the Peace's Wife
- Curt Furberg
- Foreigner
- Lisa Golm
- Yugoslav Consul's Wife
- George Guhl
- Door Attendant
- Winifred Harris
- Chairlady
- Carey Harrison
- Spaniard
- William Holmes
- Man at Banquet
- Bobby Larson
- Dickie Dunlap
- Ben Lessy
- Punchy
- Murdock MacQuarrie
- Head Copy Reader
- Edward McWade
- Adolph
- Frank Mills
- Mug
- Gerald Mohr
- Radio Emcee
- Amber Norman
- Showgirl
- Sergio Orta
- Mr. Yes
- George Ovey
- Little Sports Reporter
- Bob Perry
- Referee
- Eleni Qirici
- Girl
- Fred Rapport
- Reporter
- Jack Raymond
- Mug
- Cyril Ring
- Mr. Harding's Chauffeur
- Julian Rivero
- Spaniard
- Henry Roquemore
- Marcus P. Calverton - Justice of the Peace
- Sam Savitsky
- Russian Party Guest
- Cy Schindell
- Pinkie's Listener in Bar
- Harry Semels
- Mug
- John Sheehan
- Red Face
- Eddie Lou Simms
- Champ
- Walter O. Stahl
- Yugoslav Consul
- Charles Sullivan
- Cabby
- Ray Teal
- Married Sports Reporter
- Harry Tenbrook
- Mug
- Michael Visaroff
- Russian Guest
- Larry Wheat
- Reporter at Baseball Game
- Harry Wilson
- Lubbeck's Bodyguard
- Duke York
- Football Player
- Joe Yule
- Building Superintendent
