- Kamal Haasan
- Rajaraman Venkatraman (Vasool Raja)
- Sneha
- Janaki Vishwanathan (Paapu)
- Prabhu
- Vatti
- Prakash Raj
- Dr. Vishvanath
- Nagesh
- Raja's father
- Jayasurya
- Zahir
- Karunas
- Amit
- Crazy Mohan
- Margabandhu
- Rohini Hattangadi
- Raja's mother
- Kaka Radhakrishnan
- Margabandhu's father
- Madhan Bob
- Vasoolraja's client
- Santhana Bharathi
- Gangadharan
- Vaiyapuri
- Piles Patient
- Chitra Lakshmanan
- Doctor / Professor
- Ajay Ratnam
- Doctor / Professor
- Boys Rajan
- Professor
- Karate Raja
- Vasoolraja's sidekick
- Sukumar
- Vasoolraja's sidekick
- Benjamin
- Pick-Pocket
- Nitin Sathya
- Neelakandan
- Meera Krishnan
- (as Meera Krishna)
- Sampath Ram
- Vasoolraja's Sidekick
- Ragasiya
- Special Appearance (song 'Seena Thaana')
- Malavika
- Priya
- Mythili
- Nurse
- Kaajal Pasupathi
- Nurse
- A.K. Veeraswamy
- Janitor
